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Allergy
The European Journal of Allergy and Clinical Immunology (Allergy) is an official EAACI journal published by Wiley-Blackwell.
Allergy is one of the leading journals in the field of Allergy and Clinical Immunology, ranking 4th in Allergy and 25th in Immunology, and with an impact factor of 6.048.From 2018 onwards, Allergy has a new Editor in Chief, Prof. Cezmi Akdis. With his outstanding scientific achievements and longstanding expertise in the publication sector he will foster and expand the high quality of the journal and adapt to future challenges of outreach activities. Maria Jose Torres, as Editor Deputy, will also provide her expertise in clinical allergology to Allergy.We thereby take this opportunity to thank the past Editors in Chief, Thomas Bieber and Hans-Uwe Simon, who have been dedicated to our EAACI Journal Allergy for the last eight years. Due to their continuous personal engagement, they have increased and maintained the impact factor of our journal throughout their mandate.To go the journal's website, please click here.
Subscription to Allergy is included in the EAACI membership. Members can access the full text through the Members Area.Last updated: 26 November 2018 -
Highlights October 2018
Allergen immunotherapy in people, dogs, cats and horses – differences, similarities and research needs
Mueller RS, Jensen‐Jarolim E, Roth‐Walter F, et al. Allergy. 2018;00:1–11.
doi.org/10.1111
Probiotics for the airways: Potential to improve epithelial and immune homeostasis
Martens K, Pugin B, De Boeck I, et al. Allergy. 2018;00:1–10.
doi.org/10.1111/all.13495
Precision medicine in united airways disease: A “treatable traits” approach
Yii ACA, Tay T‐R, Choo XN, Koh MSY, Tee AKH, Wang D‐Y. Allergy. 2018;00:1–15. doi.org/10.1111/all.13496Last updated: 15 October 2018 -
Highlights September 2018
Table of Contents
Clinical trials in allergen immunotherapy: current concepts and future needs
Pfaar O, Alvaro M, Cardona V, et al. Allergy. 2018;73:1775–1783.
doi.org/10.1111
Nasal hyperreactivity in rhinitis: A diagnostic and therapeutic challenge
Van Gerven L, Steelant B, Hellings PW. Allergy. 2018;73:1784–1791.
doi.org/10.1111/all.13453
The urgent need for a harmonized severity scoring system for acute allergic reactions
Muraro A, Fernandez‐Rivas M, Beyer K, et al. Allergy. 2018;73:1792–1800.doi.org/10.1111/all.13408Last updated: 15 October 2018 -
Highlights August 2018
Table of Contents
The international WAO/EAACI guideline for the management of hereditary angioedema—The 2017 revision and update
M. Maurer, M. Magerl, I. Ansotegui, et. al. Allergy. 2018;73:1575-1596
DOI: 10.1111/all.13384
EAACI Position paper on the standardization of nasal allergen challenges
J. Augé, J. Vent, I. Agache, et. al. Allergy. 2018;73:1597-1608
DOI: 10.1111/all.13416
Daily allergic multimorbidity in rhinitis using mobile technology: A novel concept of the MASK study
J. Bousquet, P. Devillier, J. M. Anto, et. al. Allergy. 2018;73:1622-1631
DOI: 10.1111/all.13448Last updated: 16 August 2018 -
Highlights July 2018
Table of Contents
The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria
T. Zuberbier, W. Aberer, R. Asero, et. al. Allergy. 2018;73:1393‐1414.
DOI: 10.1111/all.13397
Tumor necrosis factor family member LIGHT acts with IL‐1β and TGF‐β to promote airway remodeling during rhinovirus infection
A. K. Mehta, T. Doherty, D. Broide, et. al. Allergy. 2018;73:1415–1424.
DOI: 10.1111/all.13390
Early‐life gut microbiome and egg allergy
M. Fazlollahi, Y. Chun, A. Grishin, et. al. Allergy. 2018;73:1515–1524.
DOI: 10.1111/all.13389Last updated: 16 August 2018 -
Highlights June 2018
Table of Contents
Influenza burden, prevention, and treatment in asthma‐A scoping review by the EAACI Influenza in asthma task force
J. Schwarze, P. Openshaw, A. Jha, et. al. Allergy. 2018;73:1151-1180.
DOI: 10.1111/all.13333
Lolium perenne peptide immunotherapy is well tolerated and elicits a protective B‐cell response in seasonal allergic rhinitis patients
R. Mösges, A. F. Koch, E. Raskopf, et. al. Allergy. 2018;73:1254-1262.
DOI: 10.1111/all.13392
Factors increasing the risk for a severe reaction in anaphylaxis: An analysis of data from The European Anaphylaxis Registry
M. Worm, W. Francuzik, J.‐M. Renaudin, et. al. Allergy. 2018;73:1322-1330.
DOI: 10.1111/all.13380Last updated: 25 June 2018 -
Highlights May 2018
Table of Contents
Characterization of epitope specificities of reference antibodies used for the quantification of the birch pollen allergen Bet v 1
S. Brier, M. Le Mignon, K. Jain, et. al. Allergy. 2018;73:1032–1040.
DOI: 10.1111/all.13364
MP29‐02 reduces nasal hyperreactivity and nasal mediators in patients with house dust mite‐allergic rhinitis
I. Kortekaas Krohn, I. Callebaut, Y. A. Alpizar, et. al. Allergy. 2018;73:1084–1093.
DOI: 10.1111/all.13349
Upper and lower airway remodelling mechanisms in asthma, allergic rhinitis and chronic rhinosinusitis: The one airway concept revisited
K. Samitas, A. Carter, H. H. Kariyawasam, et. al. Allergy. 2018;73:993–1002.
DOI: 10.1111/all.13373Last updated: 25 June 2018 -
Highlights April 2018
Oral myeloid cells uptake allergoids coupled to mannan driving Th1/Treg responses upon sublingual delivery in mice
I. Soria, J. López‐Relaño, M. Viñuela, et. al. Allergy. 2018;73:875–884.
DOI: 10.1111/all.13396Systemic IL‐2/anti‐IL‐2Ab complex combined with sublingual immunotherapy suppresses experimental food allergy in mice through induction of mucosal regulatory T cells
P. L. Smaldini, F. Trejo, J. L. Cohen, et. al. Allergy. 2018;73:885–895.
DOI: 10.1111/all.13402
Specific immunotherapy in local allergic rhinitis: A randomized, double‐blind placebo‐controlled trial with Phleum pratense subcutaneous allergen immunotherapy
C. Rondón, N. Blanca-López, P. Campo, et. al. Allergy. 2018;73:905–915.
DOI: 10.1111/all.13350
EAACI guidelines on allergen immunotherapy: Hymenoptera venom allergy
G. J. Sturm, E.-M. Varga, G. Roberts, et. al. Allergy. 2018;73:744–764.
DOI: 10.1111/all.13262
EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis
G. Roberts, O. Pfaar, C. A. Akdis, et. al. Allergy. 2018;73:765–798.
DOI: 10.1111/all.13317
EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy
G. B. Pajno, M. Fernandez-Rivas, S. Arasi, et. al. Allergy. 2018;73:799–815.
DOI: 10.1111/all.13319Last updated: 25 June 2018 -
Highlights March 2018
Table of Contents
Alopecia areata is characterized by expansion of circulating Th2/Tc2/Th22, within the skin-homing and systemic T-cell populations
T. Czarnowicki, H. Y. He, H.-C. Wen, et. al. Allergy 2018;73:713–723.
DOI: 10.1111/all.13346
Serine protease allergen favours Th2 responses via PAR-2 and STAT3 activation in murine model
K. Agrawal, N. Arora, et. al. Allergy 2018;73:569–575.
DOI: 10.1111/all.13315
Airway pathology in severe asthma is related to airflow obstruction but not symptom control
D. S. Ferreira, R. M. Carvalho-Pinto, M. G. Gregório, et. al. Allergy 2018;73:635–643.
DOI: 10.1111/all.13323
Nasal protein profiles in work-related asthma caused by different exposures
H. Suojalehto, I. Lindström, H. Wolff, et. al. Allergy 2018;73:653–663.
DOI: 10.1111/all.13325Last updated: 25 June 2018 -
Highlights February 2018
Table of Contents
Allergens displayed on virus-like particles are highly immunogenic but fail to activate human mast cells
P. Engeroff, F. Caviezel, F Storni, et. al. Allergy 2018;73:341–349
DOI: 10.1111/all.13268
Mucocutaneous inflammation in the Ikaros Family Zinc Finger 1-keratin 5–specific transgenic mice
M. Ueta, J. Hamuro, H. Nishigaki, et. al. Allergy 2018;73:395–404
DOI: 10.1111/all.13308
Targeting histone-acetyltransferase Tat-interactive protein 60 inhibits intestinal allergy
G. Yang, B-H. Cheng, S-B Yang, et al. Allergy 2018;73:387-39
DOI: 10.1111/all.13304
Position Papers
Current practice of allergy diagnosis and the potential impact of regulation in Europe
V. Cardona, P. Demoly, S. Dreborg, et al. Allergy. 2018;73:323-327
DOI: 10.1111/all.13306
AllergoOncology: Opposite outcomes of immune tolerance in allergy and cancer
E. Jensen-Jarolim, HJ. Bax, R. Bianchini, et al. Allergy. 2018;73:328–340
DOI: 10.1111/all.13311Last updated: 25 June 2018 -
Highlights January 2018
Is the atopic march related to confounding by genetics and early-life environment? A systematic review of sibship and twin data
S. J. Khan, S. C. Dharmage, M. C. Matheson, L. C. Gurrin et. al. Allergy. 2018;73:17–28
DOI: 10.1111/all.13228
Challenges in the implementation of EAACI guidelines on allergen immunotherapy: A global perspective on the regulation of allergen products
A. Bonertz, G. C. Roberts, M. Hoefnagel, M. Timon, J. E. Slater et. al. Allergy. 2018;73:64-76. DOI: 10.1111/all.13266
House dust mites as potential carriers for IgE sensitization to bacterial antigens
S. Dzoro, I. Mittermann, Y. Resch-Marat, S. Vrtala, M. Nehr, et. al. Allergy. 2018;73:115–124.
DOI: 10.1111/all.13260Last updated: 25 June 2018 -
Previous Highlights
- DECEMBER 2017
Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis
Dhami, S., et. al. Allergy. 2017;72:1825–1848 DOI: 10.1111/all.13208
What's in a name? Atopic dermatitis or atopic eczema, but not eczema alone
Silverberg, JI., et al. Allergy. 2017;72:2026–2030 DOI: 10.1111/all.13225
Nonlesional atopic dermatitis skin shares similar T-cell clones with lesional tissues
Brunner, PW., et al. Allergy. 2017;72:2017–2025 DOI: 10.1111/all.13223
- NOVEMBER 2017
Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis
Dhami, S., et al. Allergy. 2017;72:1597–1631 DOI: 10.1111/all.13201
Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology
Hellings, PW., et al. Allergy. 2017;72:1657-1665 DOI: 10.1111/all.13200
AhR mediates an anti-inflammatory feedback mechanism in human Langerhans cells involving FcεRI and IDO
Koch, S., et al. Allergy. 2017;72:1657-1665 DOI: 10.1111/all.13170
- OCTOBER 2017
Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis
Dhami, S., et al. Allergy. 2017;72:1597–1631 DOI: 10.1111/all.13201
Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology
Hellings, PW., et al. Allergy. 2017;72:1657-1665Z DOI: 10.1111/all.1320
AhR mediates an anti-inflammatory feedback mechanism in human Langerhans cells involving FcεRI and IDO
Koch, S., et al. Allergy. 2017;72:1686–1693 DOI: 10.1111/all.13170
- SEPTEMBER 2017
Comorbidity of chronic spontaneous urticaria and autoimmune thyroid diseases: A systematic review
Kolkhir, P., et al. Allergy. 2017;72:1440–1460 DOI: 10.1111/all.13182
Prevalence of type I sensitization to alpha-gal in forest service employees and hunters
Fischer, J., et al. Allergy. 2017;72 1540–1547 DOI: 10.1111/all.13156
Work productivity in rhinitis using cell phones: The MASK pilot study
Bousquet, J., et al. Allergy. 2017;72:1475–1484 DOI: 10.1111/all.13177
- AUGUST 2017
Clinical outcomes following inpatient penicillin allergy testing: A systematic review and meta-analysis
Sacco, KA., et al. Allergy. 2017;72:1288-1296 DOI: 10.1111/all.13168
Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement
Hellings, PW., et al. Allergy. 2017;72:1297-1305 DOI: 10.1111/all.13162
Skin prick tests and specific IgE in 10-year-old children: Agreement and association with allergic diseases
Chauveau, A., et al. Allergy. 2017;72: 1365-1373 DOI: 10.1111/all.13148
- MARCH 2017
Systematic characterization of basophil anergy
Puan KJ., et al. Allergy. 2017;72: 373-384 DOI: 10.1111/all.12952
Amoxicillin haptenates intracellular proteins that can be transported in exosomes to target cells
Sanchez-Gomez FJ., et al. Allergy. 2017; 72: 385-396 DOI: 10.1111/all.12958
- FEBRUARY 2017
Allergy in severe asthma
Del Giacco SR., et al. Allergy. 2017;72: 207-220 DOI 10.1111/all.13072
Human rhinoviruses enter and induce proliferation of B lymphocytes
Aab A., et al. Allergy. 2017;72: 232-243 DOI 10.1111/all.12931
- JANUARY 2017
Allergen-specific immunotherapy: is is vaccination against toxins after all?
Bachmann & Kündig. Allergy. 2017;72: 13-23 DOI 10.1111/all.12890
Increased microRNA-323-3p in IL-22/IL-17-producing T cells and asthma: a role in the regulation of the TGF-beta pathway and IL-22 production
Kärner J., et al. Allergy. 2017;72: 55-65 DOI 10.1111/aal.12907
- DECEMBER 2016
Beneficial effect of Lactococcus lactis NCC 2287 in a murine model of eosinophilic esophagitis
Holvoet S., et al. Allergy. 2016:71: 1753-1761 DOI 10.1111/all.12951
Cross-reactivity to fish and chicken meat – a new clinical syndrome
Kuehn A., et al. Allergy. 2016;71: 1772-1781 DOI 10.1111/all.12968
- NOVEMBER 2016
A new framework for the interpretation of IgE sensitization tests
Roberts G., et al. Allergy. 2016;71: 1540-1551 DOI 10.1111/all.12939
Component-resolved analysis of IgA, IgE, and IgG4 during egg OIT identifies markers associated with sustained unresponsiveness
Wright BL., et al. Allergy. 2016;71: 1552-1560 DOI 10.1111/all.12895
- OCTOBER 2016
Viruses and bacteria in Th2.biased allergic airway disease
Lan F., et al. Allergy. 2016;71: 1381-1392 DOI 10.1111/all.12934
The minor house dust mite allergen Der p 13 is a fatty acid-binding protein and an activator of a TLR2-mediated innate immune response
Satitsuksanoa P., et al. Allergy. 2016;71: 1425-1434 DOI 10.1111/all.12899
- SEPTEMBER 2016
Microbiome and its impact on gastrointestinal atopy
Muir AB., et al. Allergy. 2016;71: 1256-1263 DOI 10.1111/all.12943
Protein profiles of CCL5, HPGDS, and NPSR1 in plasma reveal association with childhood asthma
Hamsten C., et al. Allergy. 2016;71: 1357-1361 DOI 10.1111/all.12927
- AUGUST 2016
Helminths are positively associated with atopy and wheeze in Ugandan fishing communities: results from a cross-sectional survey
Webb E.,L et al. Allergy. 2016;71: 1156-1169 DOI 10.1111/all.12867
Endotypes of pollen-food syndrome in children with seasonal allergic rhinoconjunctivitis: a molecular classification
Mastrorilli C., et al. Allergy. 2016;71: 1181-1191 DOI 10.1111/all.12888
- JULY 2016
Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice
Frei RB., et al. Allergy. 2016;71: 944-956 DOI 10.1111/all.12858
Identification of STOML2 as a putative novel asthma risk gene associated with IL6R
Revez JA., et al. Allergy. 2016;71: 1020-1030 DOI 10.1111/all.12869
- JUNE 2016
The definition, diagnostic testing, and management of chronic inducible urticarias – The EAACI/GA2LEN/EDF/UNEV consensus recommendations 2016 update and revision
Magerl M., et al. Allergy. 2016;71: 780-802 DOI 10.1111/all.12884
A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE families
Straumann A., et al. Allergy. 2016;71: 889-900 DOI 10.1111/all.12879
- MAY 2016
Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity
Simon D., et al. Allergy. 2016;71: 611-620 DOI 10.1111/all.12846
Two galactose-alpha-1,3-galactose carrying peptidases from pork kidney mediate anaphylactogenic responses in delayed meat allergy
Hilger C., et al. Allergy. 2016;71: 711-719 DOI 10.1111/all.12835
- APRIL 2016
Current and future biomarkers in allergic asthma
Zissler UM., et al. Allergy. 2016;71: 475-494 DOI 10.1111/all.12828
Histone deacetylase activity and recurrent bacterial bronchitis in severe eosinophilic asthma
Zuccaro L., et al. Allergy. 2016;71: 571-575 DOI 10.1111/all.12831
- MARCH 2016
Barrier function of the nasal mucosa in health and type-2 biased airway disease
Zhang N., et al. Allergy. 2016;71: 295-307 DOI 10.1111/all.12809
Divergent response profile in activated cord blood T cells from first-born child implies birth-order-associated in utero immune programming
Kragh M., et al. Allergy. 2016;71: 323-332 DOI 10.1111/all.12799
- FEBRUARY 2016
Allergic manifestation 15 years after early intervention with hydrolyzed formulas – the GINI study
von Berg A., et al. Allergy. 2016;71: 210-219 DOI 10.1111/all.12790
Heritability and confirmation of genetic association studies for childhood asthma in twins
Ullemar V., et al. Allergy. 2016;71: 230-238 DOI 10.1111/all.12783
- JANUARY 2016
Epitope specificity determines cross-protection of a SIT-induced IgG4 antibody
Gadermaier E., et al. Allergy. 2016;71: 36-46 DOI 10.1111/all.12710
Prenatal maternal stress and atopic diseases in the child: a systematic review of observational studies
Andersson NW., et al. Allergy. 2016;71: 15-26 DOI 10.1111/all.12762
- DECEMBER 2016
Deficiency of FHL2 attenuates airway inflammation in mice and genetic variation associates with human bronchial hyper-responsiveness
Kurakula K., et al. Allergy. 2015;70: 1531-1544 DOI 10.1111/all.12709
Foxp3+ regulatory T cells are expanded in severe atopic dermatitis patients
Roesner LM., et al. Allergy. 2015;70: 1656-1660 DOI 10.1111/all.12712
- NOVEMBER 2015
MACVIA-ARIA Sentinal NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation
Bousquet J., et al. Allergy. 2015;70: 1372-1392 DOI 10.1111/all.12686
The imagined itch: brain circuitry supporting nocebo-induced itch in atopic dermatitis patients
Napadow V., et al. Allergy. 2015;70: 1485-1492 DOI 10.1111/all.12727
- OCTOBER 2015
Pathophysiological mechanisms of exercise-induced anaphylaxis: an EAACI position paper
Ansley L., et al. Allergy. 2015;70: 1212-1221 DOI 10.1111/all.12677
Allergic sensitization is associated with inadequate antioxidant responses in mice and men
Utsch L., et al. Allergy. 2015;70: 1246-1258 DOI 10.1111/all.12674
- SEPTEMBER 2015
MicroRNA-155 modulates P2R signaling and Th2 priming of dendritic cells during allergic airway inflammation in mice
Zech A., et al. Allergy. 2015;70: 1121-1129 DOI 10.1111/all.12643
Basophils exhibit antibacterial activity through extracellular trap formation
Yousefi S., et al. Allergy. 2015;70: 1184-1188 DOI 10.1111/all.12662
- AUGUST 2015
Incidence and natural history of challenge-proven cow’s milk allergy in European children – EuroPrevall birth cohort
Schoemaker AA., et al. Allergy. 2015;70: 963-972 DOI 10.1111/all.12630
Phenotyping asthma, rhinitis and eczema in MeDALL population-based birth cohorts: an allergic comorbidity cluster
Garcia-Aymerich J., et al. Allergy. 2015;70: 973-984 DOI 10.1111/all.12640
- JULY 2015
EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders
Boyman O., et al. Allergy. 2015;70: 727-754 DOI 10.1111/all.12616
Activation of KIT modulates the function of tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) in mast cells
Förster A., et al. Allergy. 2015;70: 764-774 DOI 10.1111/all.12612
- JUNE 2015
Constructing a classification of hypersensitivity/allergic diseases for ICD-11 by crowdsourcing the allergist community
Tanno LK., et al. Allergy. 2015;70: 609-615 DOI 10.1111/all.12604
Natural clinical tolerance to peanut in African patients is caused by poor allergenic activity of peanut IgE
Wollmann E., et al. Allergy. 2015;70: 638-652 DOI 10.1111/all.12592
- MAY 2015
Phenotypes and endotypes of rhinitis and their impact on management: a PRACTALL report
Papadopoulos NG., et al. Allergy. 2015;70: 474-494 DOI 10.1111/all.12573
Comprehensive metabolomics identifies the alarmin uric acid as a critical signal for the induction of peanut allergy
Kong J., et al. Allergy. 2015;70: 495-505 DOI 10.1111/all.12579
- APRIL 2015
In vivo diagnosis of allergic diseases – allergen provocation tests
Agache I., et al. Allergy. 2015;70: 355-365 DOI 10.1111/all.12586
Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation
Simon D., et al. Allergy. 2015;70: 443-452 DOI 10.1111/all.12570
- MARCH 2015
The influence of childhood traffic-related air pollution exposure on asthma, allergy and sensitization: a systematic review and a meta-analysis of birth cohort studies
Bowatte G., et al. Allergy. 2015;70: 245-256 DOI 10.1111/all.12561
The locus C11orf30 increases susceptibility to poly-sensitization
Amaral AFS., et al. Allergy. 2015;70: 328-333 DOI 10.1111/all.12557
Last updated: 25 June 2018
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